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A dominantly negative mutation in cardiac troponin I at the interface with troponin T causes early remodeling in ventricular cardiomyocytes

We previously reported a point mutation substituting Cys for Arg(111) in the highly conserved troponin T (TnT)-contacting helix of cardiac troponin I (cTnI) in wild turkey hearts (Biesiadecki et al. J Biol Chem 279: 13825–13832, 2004). This dominantly negative TnI-TnT interface mutation decreases th...

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Bibliografski detalji
Glavni autori: Wei, Hongguang, Jin, J.-P.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137140/
https://ncbi.nlm.nih.gov/pubmed/24898585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00053.2014
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