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Cyp2c44 epoxygenase in the collecting duct is essential for the high K(+) intake-induced antihypertensive effect

Cytochrome P-450, family 2, subfamily c, polypeptide 44 (Cyp2c44) epoxygenase metabolizes arachidonic acid (AA) to epoxyeicosatrienoic acids (EETs) in kidney and vascular tissues. In the present study, we used real-time quantitative PCR techniques to examine the effect of high salt or high K(+) (HK)...

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Detalhes bibliográficos
Main Authors: Wang, Wen-Hui, Zhang, Chengbiao, Lin, Dao-Hong, Wang, Lijun, Graves, Joan P., Zeldin, Darryl C., Capdevila, Jorge H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137132/
https://ncbi.nlm.nih.gov/pubmed/24966089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00123.2014
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