A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A

Kinetochores are megadalton-sized protein complexes that mediate chromosome–microtubule interactions in eukaryotes. How kinetochore assembly is triggered specifically on centromeric chromatin is poorly understood. Here we use biochemical reconstitution experiments alongside genetic and structural an...

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Détails bibliographiques
Auteurs principaux: Hornung, Peter, Troc, Paulina, Malvezzi, Francesca, Maier, Michael, Demianova, Zuzana, Zimniak, Tomasz, Litos, Gabriele, Lampert, Fabienne, Schleiffer, Alexander, Brunner, Matthias, Mechtler, Karl, Herzog, Franz, Marlovits, Thomas C., Westermann, Stefan
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2014
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137059/
https://ncbi.nlm.nih.gov/pubmed/25135934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403081
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