A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A

Kinetochores are megadalton-sized protein complexes that mediate chromosome–microtubule interactions in eukaryotes. How kinetochore assembly is triggered specifically on centromeric chromatin is poorly understood. Here we use biochemical reconstitution experiments alongside genetic and structural an...

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Библиографические подробности
Главные авторы: Hornung, Peter, Troc, Paulina, Malvezzi, Francesca, Maier, Michael, Demianova, Zuzana, Zimniak, Tomasz, Litos, Gabriele, Lampert, Fabienne, Schleiffer, Alexander, Brunner, Matthias, Mechtler, Karl, Herzog, Franz, Marlovits, Thomas C., Westermann, Stefan
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2014
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137059/
https://ncbi.nlm.nih.gov/pubmed/25135934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403081
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