A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A

Kinetochores are megadalton-sized protein complexes that mediate chromosome–microtubule interactions in eukaryotes. How kinetochore assembly is triggered specifically on centromeric chromatin is poorly understood. Here we use biochemical reconstitution experiments alongside genetic and structural an...

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Autori principali: Hornung, Peter, Troc, Paulina, Malvezzi, Francesca, Maier, Michael, Demianova, Zuzana, Zimniak, Tomasz, Litos, Gabriele, Lampert, Fabienne, Schleiffer, Alexander, Brunner, Matthias, Mechtler, Karl, Herzog, Franz, Marlovits, Thomas C., Westermann, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137059/
https://ncbi.nlm.nih.gov/pubmed/25135934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403081
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