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A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A

Kinetochores are megadalton-sized protein complexes that mediate chromosome–microtubule interactions in eukaryotes. How kinetochore assembly is triggered specifically on centromeric chromatin is poorly understood. Here we use biochemical reconstitution experiments alongside genetic and structural an...

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Detalhes bibliográficos
Main Authors: Hornung, Peter, Troc, Paulina, Malvezzi, Francesca, Maier, Michael, Demianova, Zuzana, Zimniak, Tomasz, Litos, Gabriele, Lampert, Fabienne, Schleiffer, Alexander, Brunner, Matthias, Mechtler, Karl, Herzog, Franz, Marlovits, Thomas C., Westermann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137059/
https://ncbi.nlm.nih.gov/pubmed/25135934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403081
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