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A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors

The Ndc80 complex is the key microtubule-binding element of the kinetochore. In contrast to the well-characterized interaction of Ndc80-Nuf2 heads with microtubules, little is known about how the Spc24-25 heterodimer connects to centromeric chromatin. Here, we present molecular details of Spc24-25 i...

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Detalhes bibliográficos
Main Authors: Malvezzi, Francesca, Litos, Gabriele, Schleiffer, Alexander, Heuck, Alexander, Mechtler, Karl, Clausen, Tim, Westermann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567489/
https://ncbi.nlm.nih.gov/pubmed/23334295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.356
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