Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic Shock

BACKGROUND: Previous investigations and meta-analyses on the effect of glucocorticoids on mortality in septic shock revealed mixed results. This heterogeneity might be evoked by genetic variations. Such candidate is a promoter polymorphism (-94ins/delATTG) of the gene encoding the ubiquitous transcr...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Schäfer, Simon T., Gessner, Sophia, Scherag, André, Rump, Katharina, Frey, Ulrich H., Siffert, Winfried, Westendorf, Astrid M., Steinmann, Jörg, Peters, Jürgen, Adamzik, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136840/
https://ncbi.nlm.nih.gov/pubmed/25133403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104953
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items