Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic Shock

BACKGROUND: Previous investigations and meta-analyses on the effect of glucocorticoids on mortality in septic shock revealed mixed results. This heterogeneity might be evoked by genetic variations. Such candidate is a promoter polymorphism (-94ins/delATTG) of the gene encoding the ubiquitous transcr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schäfer, Simon T., Gessner, Sophia, Scherag, André, Rump, Katharina, Frey, Ulrich H., Siffert, Winfried, Westendorf, Astrid M., Steinmann, Jörg, Peters, Jürgen, Adamzik, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136840/
https://ncbi.nlm.nih.gov/pubmed/25133403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104953
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados