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Putative Kappa Opioid Heteromers As Targets for Developing Analgesics Free of Adverse Effects

[Image: see text] It is now generally recognized that upon activation by an agonist, β-arrestin associates with G protein-coupled receptors and acts as a scaffold in creating a diverse signaling network that could lead to adverse effects. As an approach to reducing side effects associated with κ opi...

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Detalhes bibliográficos
Main Authors: Le Naour, Morgan, Lunzer, Mary M., Powers, Michael D., Kalyuzhny, Alexander E., Benneyworth, Michael A., Thomas, Mark J., Portoghese, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136663/
https://ncbi.nlm.nih.gov/pubmed/24978316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500159d
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