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Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA

[Image: see text] Ribonucleoside analogues bearing terminal alkynes, including 7-ethynyl-8-aza-7-deazaadenosine (7-EAA), are useful for RNA modification applications. However, although alkyne- and triazole-bearing ribonucleosides are in widespread use, very little information is available on the imp...

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Detalhes bibliográficos
Main Authors: Phelps, Kelly J., Ibarra-Soza, José M., Tran, Kiet, Fisher, Andrew J., Beal, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136661/
https://ncbi.nlm.nih.gov/pubmed/24896732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500270x
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