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Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation
The discovery of Ten Eleven Translocation proteins, enzymes that oxidize 5-methylcytosine (5mC) in DNA, has revealed novel mechanisms for the regulation of DNA methylation. We have mapped 5-hydroxymethylcytosine (5hmC) at different stages of T-cell development in the thymus and T-cell differentiatio...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136618/ https://ncbi.nlm.nih.gov/pubmed/25071199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412327111 |
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