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Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance
Many cancers exhibit sensitivity to the inhibition of a single genetic lesion, a property that has been successfully exploited with oncogene-targeted therapeutics. However, inhibition of single oncogenes often fails to result in sustained tumor regression due to the emergence of therapy-resistant ce...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136575/ https://ncbi.nlm.nih.gov/pubmed/25071175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406123111 |
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