Llwytho...

Histone Deacetylase Inhibitor Sensitizes Apoptosis-resistant Melanomas to Cytotoxic Human T Lymphocytes through Regulation of TRAIL/DR5 Pathway

Modern immune therapies [PD-1/PD-L1 and CTLA-4 checkpoints blockade, and adoptive cell transfer (ACT)] have remarkably improved the response rates of metastatic melanoma. These modalities rely on the killing potential of cytotoxic T lymphocytes (CTL) as proximal mediator of anti-melanoma responses....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jazirehi, Ali R., Kurdistani, Siavash K., Economou, James S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136528/
https://ncbi.nlm.nih.gov/pubmed/24639349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302532
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