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A Mouse Model to Evaluate the Impact of Species, Sex, and Lipid Load on Lymphatic Drug Transport

PURPOSE: To establish a lymph-cannulated mouse model, and use the model to investigate the impact of lipid dose on exogenous and endogenous lipid recruitment, and drug transport, into the lymph of males versus females. Finally, lymphatic transport and drug absorption in the mouse were compared to ot...

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書誌詳細
主要な著者: Trevaskis, Natalie L., Caliph, Suzanne M., Nguyen, Gary, Tso, Patrick, Charman, William N., Porter, Christopher J. H.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136478/
https://ncbi.nlm.nih.gov/pubmed/23430484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1000-0
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