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Differentiation of Histidine Tautomeric States using (15)N Selectively Filtered (13)C Solid-State NMR Spectroscopy
The histidine imidazole ring in proteins usually contains a mixture of three possible tautomeric states (two neutral - τ and π states and a charged state) at physiological pHs. Differentiating the tautomeric states is critical for understanding how the histidine residue participates in many structur...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136442/ https://ncbi.nlm.nih.gov/pubmed/25026459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2014.06.005 |
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