Cytomegalovirus Contributes to Glioblastoma in the Context of Tumor Suppressor Mutations

To study the controversial role of cytomegalovirus (CMV) in glioblastoma, we assessed the effects of murine CMV (MCMV) perinatal infection in a GFAP-cre; Nf1(loxP/+); Trp53(−/+) genetic mouse model of glioma (Mut3 mice). Early on after infection, MCMV antigen was predominantly localized in CD45+ lym...

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Autori principali: Price, Richard L., Song, Jieun, Bingmer, Katherine, Kim, Tae Hyong, Yi, Ji-Yeun, Nowicki, Michal O., Mo, Xiaokui, Hollon, Todd, Murnan, Eric, Alvarez-Breckenridge, Christopher, Fernandez, Soledad, Kaur, Balveen, Rivera, Andreana, Oglesbee, Michael, Cook, Charles, Chiocca, E. Antonio, Kwon, Chang-Hyuk
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136413/
https://ncbi.nlm.nih.gov/pubmed/23729642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3846
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