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Cytomegalovirus Contributes to Glioblastoma in the Context of Tumor Suppressor Mutations

To study the controversial role of cytomegalovirus (CMV) in glioblastoma, we assessed the effects of murine CMV (MCMV) perinatal infection in a GFAP-cre; Nf1(loxP/+); Trp53(−/+) genetic mouse model of glioma (Mut3 mice). Early on after infection, MCMV antigen was predominantly localized in CD45+ lym...

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Detalhes bibliográficos
Main Authors: Price, Richard L., Song, Jieun, Bingmer, Katherine, Kim, Tae Hyong, Yi, Ji-Yeun, Nowicki, Michal O., Mo, Xiaokui, Hollon, Todd, Murnan, Eric, Alvarez-Breckenridge, Christopher, Fernandez, Soledad, Kaur, Balveen, Rivera, Andreana, Oglesbee, Michael, Cook, Charles, Chiocca, E. Antonio, Kwon, Chang-Hyuk
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136413/
https://ncbi.nlm.nih.gov/pubmed/23729642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3846
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