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Biosynthesis of nitric oxide activates iron regulatory factor in macrophages.

Biosynthesis of nitric oxide (NO) from L-arginine modulates activity of iron-dependent enzymes, including mitochondrial acontiase, an [Fe-S] protein. We examined the effect of NO on the activity of iron regulatory factor (IRF), a cytoplasmic protein which modulates both ferritin mRNA translation and...

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Udgivet i:EMBO J
Principais autores: Drapier, J C, Hirling, H, Wietzerbin, J, Kaldy, P, Kühn, L C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413640/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06038.x
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