Biosynthesis of nitric oxide activates iron regulatory factor in macrophages.

Biosynthesis of nitric oxide (NO) from L-arginine modulates activity of iron-dependent enzymes, including mitochondrial acontiase, an [Fe-S] protein. We examined the effect of NO on the activity of iron regulatory factor (IRF), a cytoplasmic protein which modulates both ferritin mRNA translation and...

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Autors principals: Drapier, J C, Hirling, H, Wietzerbin, J, Kaldy, P, Kühn, L C
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC413640/
https://ncbi.nlm.nih.gov/pubmed/7504626
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