Activation of iron regulatory protein-1 by oxidative stress in vitro
Iron regulatory protein-1 (IRP-1), a central cytoplasmic regulator of cellular iron metabolism, is rapidly activated by oxidative stress to bind to mRNA iron-responsive elements. We have reconstituted the response of IRP-1 to extracellular H(2)O(2) in a system derived from murine B6 fibroblasts perm...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10559 |
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