Loading...
Activation of iron regulatory protein-1 by oxidative stress in vitro
Iron regulatory protein-1 (IRP-1), a central cytoplasmic regulator of cellular iron metabolism, is rapidly activated by oxidative stress to bind to mRNA iron-responsive elements. We have reconstituted the response of IRP-1 to extracellular H(2)O(2) in a system derived from murine B6 fibroblasts perm...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
1998
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC27933/ https://ncbi.nlm.nih.gov/pubmed/9724742 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|