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CD4 Ligation on Human Blood Monocytes Triggers Macrophage Differentiation and Enhances HIV Infection

A unique aspect of human monocytes, compared to monocytes from many other species, is that they express the CD4 molecule. However, the role of the CD4 molecule in human monocyte development and function is not known. We determined that the activation of CD4 via interaction with major histocompatibil...

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Autori principali: Zhen, Anjie, Krutzik, Stephan R., Levin, Bernard R., Kasparian, Saro, Zack, Jerome A., Kitchen, Scott G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136363/
https://ncbi.nlm.nih.gov/pubmed/24942581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00616-14
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