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CD4 Ligation on Human Blood Monocytes Triggers Macrophage Differentiation and Enhances HIV Infection

A unique aspect of human monocytes, compared to monocytes from many other species, is that they express the CD4 molecule. However, the role of the CD4 molecule in human monocyte development and function is not known. We determined that the activation of CD4 via interaction with major histocompatibil...

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Detalhes bibliográficos
Main Authors: Zhen, Anjie, Krutzik, Stephan R., Levin, Bernard R., Kasparian, Saro, Zack, Jerome A., Kitchen, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136363/
https://ncbi.nlm.nih.gov/pubmed/24942581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00616-14
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