Long-Term Antiretroviral Treatment Initiated at Primary HIV-1 Infection Affects the Size, Composition, and Decay Kinetics of the Reservoir of HIV-1-Infected CD4 T Cells

Initiation of antiretroviral therapy during the earliest stages of HIV-1 infection may limit the seeding of a long-lasting viral reservoir, but long-term effects of early antiretroviral treatment initiation remain unknown. Here, we analyzed immunological and virological characteristics of nine patie...

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Main Authors: Buzon, Maria J., Martin-Gayo, Enrique, Pereyra, Florencia, Ouyang, Zhengyu, Sun, Hong, Li, Jonathan Z., Piovoso, Michael, Shaw, Amy, Dalmau, Judith, Zangger, Nadine, Martinez-Picado, Javier, Zurakowski, Ryan, Yu, Xu G., Telenti, Amalio, Walker, Bruce D., Rosenberg, Eric S., Lichterfeld, Mathias
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136362/
https://ncbi.nlm.nih.gov/pubmed/24965451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01046-14
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