Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF.

We have used protection against ribonuclease H to investigate the mechanisms by which U1 small nuclear ribonucleoprotein particles (snRNPs) determine the use of two alternative 5' splice sites. The initial binding of U1 snRNPs to alternative consensus splice sites was indiscriminate, and on a h...

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Publicat a:EMBO J
Autors principals: Eperon, I C, Ireland, D C, Smith, R A, Mayeda, A, Krainer, A R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8253084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06034.x
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