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Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF.

We have used protection against ribonuclease H to investigate the mechanisms by which U1 small nuclear ribonucleoprotein particles (snRNPs) determine the use of two alternative 5' splice sites. The initial binding of U1 snRNPs to alternative consensus splice sites was indiscriminate, and on a h...

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Detalhes bibliográficos
Main Authors: Eperon, I C, Ireland, D C, Smith, R A, Mayeda, A, Krainer, A R
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413636/
https://ncbi.nlm.nih.gov/pubmed/8253084
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