Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF.

We have used protection against ribonuclease H to investigate the mechanisms by which U1 small nuclear ribonucleoprotein particles (snRNPs) determine the use of two alternative 5' splice sites. The initial binding of U1 snRNPs to alternative consensus splice sites was indiscriminate, and on a h...

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Vydáno v:EMBO J
Hlavní autoři: Eperon, I C, Ireland, D C, Smith, R A, Mayeda, A, Krainer, A R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8253084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06034.x
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