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HIV-1 and HIV-2 Vif Interact with Human APOBEC3 Proteins Using Completely Different Determinants

Human APOBEC3 (A3) restriction factors provide intrinsic immunity against zoonotic transmission of pathogenic viruses. A3D, A3F, A3G, and A3H haplotype II (A3H-hapII) can be packaged into virion infectivity factor (Vif)-deficient HIVs to inhibit viral replication. To overcome these restriction facto...

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Bibliografski detalji
Glavni autori: Smith, Jessica L., Izumi, Taisuke, Borbet, Timothy C., Hagedorn, Ariel N., Pathak, Vinay K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136346/
https://ncbi.nlm.nih.gov/pubmed/24942576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01318-14
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