Wird geladen...
Hepatitis A Virus 3C Protease Cleaves NEMO To Impair Induction of Beta Interferon
NEMO (NF-κB essential modulator) is a bridging adaptor indispensable for viral activation of interferon (IFN) antiviral response. Herein, we show that hepatitis A virus (HAV) 3C protease (3C(pro)) cleaves NEMO at the Q304 residue, negating its signaling adaptor function and abrogating viral inductio...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2014
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136334/ https://ncbi.nlm.nih.gov/pubmed/24920812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00869-14 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|