SAMHD1 Specifically Affects the Antiviral Potency of Thymidine Analog HIV Reverse Transcriptase Inhibitors

Sterile alpha motif and histidine-aspartic domain-containing protein 1 (SAMHD1) is a deoxynucleoside triphosphate (dNTP) triphosphohydrolase recently recognized as an antiviral factor that acts by depleting dNTP availability for viral reverse transcriptase (RT). SAMHD1 restriction is counteracted by...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ballana, Ester, Badia, Roger, Terradas, Gerard, Torres-Torronteras, Javier, Ruiz, Alba, Pauls, Eduardo, Riveira-Muñoz, Eva, Clotet, Bonaventura, Martí, Ramon, Esté, José A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136047/
https://ncbi.nlm.nih.gov/pubmed/24913159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03145-14
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars