Radicicol Confers Mid-Schizont Arrest by Inhibiting Mitochondrial Replication in Plasmodium falciparum

Radicicol, an antifungal antibiotic, was previously identified as a compound having antimalarial activity. However, its mechanism of action in Plasmodium falciparum was not elucidated. While characterizing its antimalarial function, we observed that radicicol manifested two distinct developmental de...

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Bibliografiske detaljer
Main Authors: Chalapareddy, Sureshkumar, Bhattacharyya, Mrinal Kanti, Mishra, Seema, Bhattacharyya, Sunanda
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136038/
https://ncbi.nlm.nih.gov/pubmed/24841259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02519-13
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