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Radicicol-Mediated Inhibition of Topoisomerase VIB-VIA Activity of the Human Malaria Parasite Plasmodium falciparum

Plasmodium falciparum topoisomerase VIB (TopoVIB)-TopoVIA (TopoVIB-VIA) complex can be potentially exploited as a drug target against malaria due to its absence from the human genome. Previous work in our laboratory has suggested that P. falciparum TopoVIB (PfTopoVIB) might be a target of radicicol...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Chalapareddy, Sureshkumar, Chakrabarty, Swati, Bhattacharyya, Mrinal Kanti, Bhattacharyya, Sunanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863635/
https://ncbi.nlm.nih.gov/pubmed/27303712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00025-15
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