Antiherpesvirus Activities of Two Novel 4′-Thiothymidine Derivatives, KAY-2-41 and KAH-39-149, Are Dependent on Viral and Cellular Thymidine Kinases

The emergence of drug-resistant herpesviruses represents a significant problem in clinical practice, primarily in immunocompromised patients. Furthermore, effective antiviral therapies against gammaherpesvirus-associated diseases are lacking. Here, we present two thiothymidine derivatives, KAY-2-41...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Coen, Natacha, Duraffour, Sophie, Haraguchi, Kazuhiro, Balzarini, Jan, van den Oord, Joost J., Snoeck, Robert, Andrei, Graciela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136010/
https://ncbi.nlm.nih.gov/pubmed/24820089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02825-14
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak