KAY-2-41, a Novel Nucleoside Analogue Inhibitor of Orthopoxviruses In Vitro and In Vivo

The availability of adequate treatments for poxvirus infections would be valuable not only for human use but also for veterinary use. In the search for novel antiviral agents, a 1′-methyl-substituted 4′-thiothymidine nucleoside, designated KAY-2-41, emerged as an efficient inhibitor of poxviruses. I...

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Detalhes bibliográficos
Main Authors: Duraffour, Sophie, Drillien, Robert, Haraguchi, Kazuhiro, Balzarini, Jan, Topalis, Dimitri, van den Oord, Joost J., Andrei, Graciela, Snoeck, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910790/
https://ncbi.nlm.nih.gov/pubmed/24126587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01601-13
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