KAY-2-41, a Novel Nucleoside Analogue Inhibitor of Orthopoxviruses In Vitro and In Vivo

The availability of adequate treatments for poxvirus infections would be valuable not only for human use but also for veterinary use. In the search for novel antiviral agents, a 1′-methyl-substituted 4′-thiothymidine nucleoside, designated KAY-2-41, emerged as an efficient inhibitor of poxviruses. I...

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Main Authors: Duraffour, Sophie, Drillien, Robert, Haraguchi, Kazuhiro, Balzarini, Jan, Topalis, Dimitri, van den Oord, Joost J., Andrei, Graciela, Snoeck, Robert
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910790/
https://ncbi.nlm.nih.gov/pubmed/24126587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01601-13
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