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Type I Interferon Mimetics Bypass Vaccinia Virus Decoy Receptor Virulence Factor for Protection of Mice against Lethal Infection

The canonical model of interferon (IFN) signaling focuses solely on the activation of STAT transcription factors which, according to the model, are initiated by the singular event of cross-linkage of the receptor extracellular domain by the IFN. The IFN has no further function beyond this. The model...

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Detalhes bibliográficos
Main Authors: Ahmed, Chulbul M., Johnson, Howard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135919/
https://ncbi.nlm.nih.gov/pubmed/24964806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00204-14
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