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Signaling of Chloroquine-Induced Stress in the Yeast Saccharomyces cerevisiae Requires the Hog1 and Slt2 Mitogen-Activated Protein Kinase Pathways

Chloroquine (CQ) has been under clinical use for several decades, and yet little is known about CQ sensing and signaling mechanisms or about their impact on various biological pathways. We employed the budding yeast Saccharomyces cerevisiae as a model organism to study the pathways targeted by CQ. O...

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Bibliografiske detaljer
Main Authors: Baranwal, Shivani, Azad, Gajendra Kumar, Singh, Vikash, Tomar, Raghuvir S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135872/
https://ncbi.nlm.nih.gov/pubmed/25022582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02393-13
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