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Signaling of Chloroquine-Induced Stress in the Yeast Saccharomyces cerevisiae Requires the Hog1 and Slt2 Mitogen-Activated Protein Kinase Pathways

Chloroquine (CQ) has been under clinical use for several decades, and yet little is known about CQ sensing and signaling mechanisms or about their impact on various biological pathways. We employed the budding yeast Saccharomyces cerevisiae as a model organism to study the pathways targeted by CQ. O...

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Detalhes bibliográficos
Main Authors: Baranwal, Shivani, Azad, Gajendra Kumar, Singh, Vikash, Tomar, Raghuvir S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135872/
https://ncbi.nlm.nih.gov/pubmed/25022582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02393-13
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