Efficacy of Fosfomycin Compared to Vancomycin in Treatment of Implant-Associated Chronic Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats

Fosfomycin monotherapy was compared to therapy with vancomycin for the treatment of implant-associated methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis in an experimental rat model. The proximal tibiae were inoculated with 15 μl of a suspension containing 1 × 10(8) to 5 × 10(8) CFU/m...

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Main Authors: Poeppl, Wolfgang, Lingscheid, Tilman, Bernitzky, Dominik, Schwarze, Uwe Y., Donath, Oliver, Perkmann, Thomas, Kozakowski, Nicolas, Plasenzotti, Roberto, Reznicek, Gottfried, Burgmann, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135863/
https://ncbi.nlm.nih.gov/pubmed/24936591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02720-13
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