Daptomycin, Fosfomycin, or Both for Treatment of Methicillin-Resistant Staphylococcus aureus Osteomyelitis in an Experimental Rat Model

The in vivo activities of daptomycin, fosfomycin, and a combination of both antibiotics against a clinical isolate of methicillin-resistant Staphylococcus aureus (daptomycin MIC, 0.25 μg/ml; fosfomycin MIC, 0.5 μg/ml) were evaluated in a rat model of osteomyelitis. A total of 37 rats with experiment...

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Detalhes bibliográficos
Main Authors: Poeppl, W., Tobudic, S., Lingscheid, T., Plasenzotti, R., Kozakowski, N., Lagler, H., Georgopoulos, A., Burgmann, H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194995/
https://ncbi.nlm.nih.gov/pubmed/21859942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00584-11
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