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Daptomycin plus Fosfomycin, a Synergistic Combination in Experimental Implant-Associated Osteomyelitis Due to Methicillin-Resistant Staphylococcus aureus in Rats

The aim of this study was to evaluate the combination of daptomycin and fosfomycin in experimental chronic implant-associated osteomyelitis due to methicillin-resistant Staphylococcus aureus (MRSA). Infection was induced in the tibiae of rats by the insertion of a bacterial inoculum (1 to 5 × 10(8)...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lingscheid, Tilman, Poeppl, Wolfgang, Bernitzky, Dominik, Veletzky, Luzia, Kussmann, Manuel, Plasenzotti, Roberto, Burgmann, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335895/
https://ncbi.nlm.nih.gov/pubmed/25403675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04246-14
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