Fosmidomycin Decreases Membrane Hopanoids and Potentiates the Effects of Colistin on Burkholderia multivorans Clinical Isolates

Burkholderia cepacia complex (Bcc) pulmonary infections in people living with cystic fibrosis (CF) are difficult to treat because of the extreme intrinsic resistance of most isolates to a broad range of antimicrobials. Fosmidomycin is an antibacterial and antiparasitic agent that disrupts the isopre...

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Autors principals: Malott, Rebecca J., Wu, Chia-Hung, Lee, Tracy D., Hird, Trevor J., Dalleska, Nathan F., Zlosnik, James E. A., Newman, Dianne K., Speert, David P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135860/
https://ncbi.nlm.nih.gov/pubmed/24957830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02705-14
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