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Fosmidomycin Decreases Membrane Hopanoids and Potentiates the Effects of Colistin on Burkholderia multivorans Clinical Isolates

Burkholderia cepacia complex (Bcc) pulmonary infections in people living with cystic fibrosis (CF) are difficult to treat because of the extreme intrinsic resistance of most isolates to a broad range of antimicrobials. Fosmidomycin is an antibacterial and antiparasitic agent that disrupts the isopre...

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Detalhes bibliográficos
Main Authors: Malott, Rebecca J., Wu, Chia-Hung, Lee, Tracy D., Hird, Trevor J., Dalleska, Nathan F., Zlosnik, James E. A., Newman, Dianne K., Speert, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135860/
https://ncbi.nlm.nih.gov/pubmed/24957830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02705-14
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