First Detection of TR(46)/Y121F/T289A and TR(34)/L98H Alterations in Aspergillus fumigatus Isolates from Azole-Naive Patients in Denmark despite Negative Findings in the Environment

Azole-resistant Aspergillus fumigatus harboring the TR(34)/L98H or TR(46)/Y121F/T289A alterations is increasingly found in Europe and Asia. Here, we present the first clinical cases of TR(46)/Y121/T289A and three cases of TR(34)/L98H outside the cystic fibrosis (CF) population in Denmark and the res...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Astvad, K. M. T., Jensen, R. H., Hassan, T. M., Mathiasen, E. G., Thomsen, G. M., Pedersen, U. G., Christensen, M., Hilberg, O., Arendrup, M. C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135837/
https://ncbi.nlm.nih.gov/pubmed/24936595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02855-14
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