The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues.

Phosphorylation of Thr161, a residue conserved in all members of the cdc2 family, has been reported to be absolutely required for the catalytic activity of cdc2, the major regulator of eukaryotic cell cycle. In the present work, we have purified from starfish oocytes a kinase that specifically activ...

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Dades bibliogràfiques

Publicat a:	EMBO J
Autors principals:	Fesquet, D, Labbé, J C, Derancourt, J, Capony, J P, Galas, S, Girard, F, Lorca, T, Shuttleworth, J, Dorée, M, Cavadore, J C
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 1993
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8344251/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05980.x
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