Degradation of the proto-oncogene product p39mos is not necessary for cyclin proteolysis and exit from meiotic metaphase: requirement for a Ca(2+)-calmodulin dependent event.

Exit from M phase, which requires cyclin degradation, is prevented from occurring in unfertilized eggs of vertebrates arrested at second meiotic metaphase due to a cytostatic factor recently identified as p39mos, the product of the proto-oncogene c-mos. Calpain can destroy both p39mos and cyclin in...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Lorca, T, Galas, S, Fesquet, D, Devault, A, Cavadore, J C, Dorée, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452893/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1829675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07741.x
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