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UPC2 Is Universally Essential for Azole Antifungal Resistance in Candida albicans
In Candida albicans, the transcription factor Upc2 is central to the regulation of ergosterol biosynthesis. UPC2-activating mutations contribute to azole resistance, whereas disruption increases azole susceptibility. In the present study, we investigated the relationship of UPC2 to fluconazole susce...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135735/ https://ncbi.nlm.nih.gov/pubmed/24659578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00221-13 |
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