Spliced stromal cell-derived factor-1α analog stimulates endothelial progenitor cell migration and improves cardiac function in a dose-dependent manner after myocardial infarction

OBJECTIVES: Stromal cell-derived factor (SDF)-1α is a potent endogenous endothelial progenitor cell (EPC) chemokine and key angiogenic precursor. Recombinant SDF-1α has been demonstrated to improve neovasculogenesis and cardiac function after myocardial infarction (MI) but SDF-1α is a bulky protein...

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Autors principals: Hiesinger, William, Frederick, John R., Atluri, Pavan, McCormick, Ryan C., Marotta, Nicole, Muenzer, Jeffrey R., Woo, Y. Joseph
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135713/
https://ncbi.nlm.nih.gov/pubmed/20951261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2010.08.012
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