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The E3 Ligase CHIP Mediates Ubiquitination and Degradation of Mixed-Lineage Kinase 3
Mixed-lineage kinase 3 (MLK3) activates mitogen-activated protein kinase (MAPK) signaling pathways and has important functions in migration, invasion, proliferation, tumorigenesis, and apoptosis. We investigated the role of the E3 ligase carboxyl terminus of Hsc70-interacting protein (CHIP) in the r...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135596/ https://ncbi.nlm.nih.gov/pubmed/24912674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00296-14 |
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