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Inhibition of Cdc42-mediated activation of mixed lineage kinase 3 by the tumor suppressor protein merlin

Mammalian mitogen-activated protein kinase (MAPK) signaling pathways respond to diverse extracellular signals and coordinate a range of cellular responses. Mixed lineage kinase 3 (MLK3) is a member of the mixed lineage kinase family of MAPK kinase kinases (MAP3Ks) that functions to regulate multiple...

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Bibliographic Details
Main Authors: Zhan, Yu, Chadee, Deborah N
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116608/
https://ncbi.nlm.nih.gov/pubmed/21686274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.3.14935
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