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Mitochondrial Matrix Ca(2+) Accumulation Regulates Cytosolic NAD(+)/NADH Metabolism, Protein Acetylation, and Sirtuin Expression
Mitochondrial calcium uptake stimulates bioenergetics and drives energy production in metabolic tissue. It is unknown how a calcium-mediated acceleration in matrix bioenergetics would influence cellular metabolism in glycolytic cells that do not require mitochondria for ATP production. Using primary...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135570/ https://ncbi.nlm.nih.gov/pubmed/24865966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00068-14 |
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