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On the value of Mendelian laws of segregation in families: data quality control, imputation and beyond

When analyzing family data, we dream of perfectly informative data, even whole genome sequences (WGS) for all family members. Reality intervenes, and we find next-generation sequence (NGS) data have error, and are often too expensive or impossible to collect on everyone. Genetic Analysis Workshop 18...

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Main Authors: Blue, Elizabeth Marchani, Sun, Lei, Tintle, Nathan L., Wijsman, Ellen M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135526/
https://ncbi.nlm.nih.gov/pubmed/25112184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21821
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